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Meghan Gage Selected Research

Isoflurophate (DFP)

1/2022DFP-Induced Status Epilepticus Severity in Mixed-Sex Cohorts of Adult Rats Housed in the Same Room: Behavioral and EEG Comparisons.
1/2022Characterization of Cortical Glial Scars in the Diisopropylfluorophosphate (DFP) Rat Model of Epilepsy.
12/2021Saracatinib, a Src Tyrosine Kinase Inhibitor, as a Disease Modifier in the Rat DFP Model: Sex Differences, Neurobehavior, Gliosis, Neurodegeneration, and Nitro-Oxidative Stress.
1/2021Differential Impact of Severity and Duration of Status Epilepticus, Medical Countermeasures, and a Disease-Modifier, Saracatinib, on Brain Regions in the Rat Diisopropylfluorophosphate Model.
11/2020Diapocynin, an NADPH oxidase inhibitor, counteracts diisopropylfluorophosphate-induced long-term neurotoxicity in the rat model.
11/2020Sex as a biological variable in the rat model of diisopropylfluorophosphate-induced long-term neurotoxicity.
1/2020Inducible nitric oxide synthase inhibitor, 1400W, mitigates DFP-induced long-term neurotoxicity in the rat model.

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Meghan Gage Research Topics

Disease

8Status Epilepticus (Complex Partial Status Epilepticus)
01/2022 - 01/2020
6Gliosis
01/2022 - 01/2020
5Seizures (Absence Seizure)
01/2022 - 01/2020
2Brain Injuries (Brain Injury)
01/2021 - 01/2020
1Epilepsy (Aura)
01/2022
1Cicatrix (Scar)
01/2022

Drug/Important Bio-Agent (IBA)

7Isoflurophate (DFP)FDA Link
01/2022 - 01/2020
4OrganophosphatesIBA
01/2022 - 11/2020
3Nerve AgentsIBA
01/2022 - 01/2021
2Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA
01/2022 - 12/2021
23-nitrotyrosineIBA
12/2021 - 01/2020
2saracatinibIBA
12/2021 - 01/2021
2Diazepam (Valium)FDA LinkGeneric
01/2021 - 01/2020
2AtropineFDA LinkGeneric
01/2021 - 01/2020
2OximesIBA
01/2021 - 01/2020
2Cholinergic Agents (Cholinergics)IBA
01/2021 - 11/2020
2CytokinesIBA
11/2020 - 01/2020
2ChemokinesIBA
11/2020 - 01/2020
1Complement C3 (C3 Complement)IBA
01/2022
1Chondroitin Sulfate ProteoglycansIBA
01/2022
1src-Family KinasesIBA
12/2021
1Anticonvulsants (Antiepileptic Drugs)IBA
01/2021
1Proto-Oncogene Proteins c-fynIBA
01/2021
1SomanIBA
01/2021
1Midazolam (Versed)FDA LinkGeneric
01/2021
1Interleukin-17 (Interleukin 17)IBA
11/2020
1LeptinIBA
11/2020
1Blood Proteins (Serum Proteins)IBA
11/2020
1NitritesIBA
11/2020
1Interleukin-6 (Interleukin 6)IBA
11/2020
1InterleukinsIBA
11/2020
1Interleukin-2 (IL2)IBA
11/2020
1AcetylcholinesteraseIBA
11/2020

Therapy/Procedure

1Therapeutics
01/2020